Dennie–Marfan syndrome

Dennie–Marfan syndrome is a syndrome in which there is association of spastic paraplegia of the lower limbs and mental retardation in children with congenital syphilis. Both sexes are affected, and the onset of the disease can be acute or insidious, with slow progression from weakness to quadriplegia. Epilepsy, cataract, and nystagmus may be also be found.

The syndrome was described by Charles Clayton Dennie in 1929, and Antoine Marfan in 1936.

External links

Chagas disease (Romana's sign) · African trypanosomiasis (Winterbottom's sign) · malaria (Schüffner's dots)

bact (clas)

gr+f/gr+a(t)/gr-p(c)/gr-o

drug(J1p, w, n, m, vacc)

virs(prot)/clss

cutn/syst (hppv/hiva, infl/zost/zoon)/epon

drugJ(dnaa, rnaa, rtva, vacc)

ambz, excv, chrm (strc)

ambz, excv, chrm

Head, general	Battle's sign · Broca aphasia · Kernig's sign · Macewen's sign · Myerson's sign · Stroop test · Wada test · Dix-Hallpike test · Hirano body

Multiple sclerosis	Dawson's fingers · Lhermitte's sign · Charcot's neurologic triad · Uhthoff's phenomenon

Other	Romberg's test · increased intracranial pressure (Cushing's triad) · Miller Fisher test

Combination	Jendrassik maneuver

Lower limb	Babinski sign · Chaddock reflex · Oppenheim's sign · Westphal's sign

Upper limb	Hoffmann's sign

Other torso/limbs

Upper limb	Froment's sign · carpal tunnel syndrome (Tinel sign, Phalen maneuver)

Lower limb	Abadie's sign of tabes dorsalis · Gowers' sign · Hoover's sign · Lasègue's sign · Trendelenburg's sign

Torso	Beevor's sign

General	Todd's paresis · Jolly's test

Mental/behavioral

anat(n/s/m/p/4/e/b/d/c/a/f/l/g)/phys/devp

noco(m/d/e/h/v/s)/cong/tumr, sysi/epon, injr

proc, drug(N1A/2AB/C/3/4/7A/B/C/D)

anat(h/r/t/c/b/l/s/a)/phys(r)/devp/prot/nttr/nttm/ntrp

noco/auto/cong/tumr, sysi/epon, injr

proc, drug(N1B)

mepr

dsrd (o, p, m, p, a, d, s), sysi/epon, spvo

proc(eval/thrp), drug(N5A/5B/5C/6A/6B/6D)